Following high school, Cuba Gooding Jr. studied Japanese martial arts for three years before turning his focus toward acting. Early on, he landed guest starring roles on shows like "Hill Street Blues" (1981) and "MacGyver" (1985). His first major role was in the 1991 box office surprise Boyz n the Hood (1991). He followed this success with supporting roles in major films like A Few Good Men (1992), Lightning Jack (1994) and Outbreak (1995).

In 1996, Cuba was cast as an arrogant but loyal football player in the Tom Cruise -Cameron Crowe film Jerry Maguire (1996). The film became a huge box office smash and earned Cuba an Academy Award for Best Supporting Actor. His "Show Me The Money" line in the movie became a nationwide catchphrase. The role elevated him to superstar status, as many of Hollywood's top producers began to "show him the money" to appear in their films.

Since Jerry Maguire (1996), Cuba has managed to keep busy with a wide range of roles alongside many of Hollywood's biggest stars. Most recently, he won critical support for his portrayal of a mentally handicapped man in the heartwarming film Radio (2003), another movie about football. In 2002, he was given a star on the Hollywood Walk of Fame.